Stress Impairs Thinking Via Mania-Linked Enzyme

An errant enzyme linked to bipolar disorder, in the brain’s prefrontal cortex, impairs cognition under stress, an animal study shows. The disturbed thinking, impaired judgment, impulsivity, and distractibility seen in mania, a destructive phase of bipolar disorder, may be traceable to overactivity of protein kinase C (PKC), suggests the study.
http://www.sciencedaily.com/releases/2004/11/041103030409.htm