Scientists Identify Key Mechanism In Estrogen’s Role In Preventing Bone Loss

Scientists have uncovered a significant new link in the chain of immune system events through which estrogen prevents bone loss and that contribute to bone loss when estrogen is deficient. Through research in mice, the scientists discovered that an immune signaling molecule called type b transforming growth factor (TGFb) is responsible for a cascade of events that leads estrogen to prevent bone loss.
http://www.sciencedaily.com/releases/2004/10/041030222950.htm