Supplementation of systemic GDF11 levels reverses functional impairments and restores genomic integrity in aged muscle stem cells (satellite cells). Increased GDF11 levels also improve muscle structural and functional features and increase strength and endurance exercise capacity.
Restoring systemic GDF11 levels reverses age-related dysfunction in mouse skeletal muscle
Sinha M, Jang YC, Oh J, Khong D, Wu EY, Manohar R, et al. Science. 2014 May 9.
RELATED ARTICLES
