Rapamycin promotes the secretion of nerve growth factors and upregulated growth-associated protein 43 expression in Schwann cells without significantly affecting Schwann cell proliferation. Study suggests that rapamycin has potential application in peripheral nerve regeneration therapy.
Rapamycin promotes Schwann cell migration and nerve growth factor secretion
Liu F, Zhang H, Zhang K, Wang X, Li S, Yin Y. Neural Regen Res. 2014 Mar 15;9(6):602-9.
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