Rapamycin-fed animals show reduced the age-dependent decline in spontaneous activity, demonstrate more fitness, improved cognition and cardiovascular health, have less cancer and live substantially longer than mice fed a normal diet.
Rapamycin and Dietary Restriction Induce Metabolically Distinctive Changes in Mouse Liver
Yu Z, Wang R, Fok WC, Coles A, Salmon AB, Perez VI. J Gerontol A Biol Sci Med Sci. 2014 Apr 22.
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