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Pulsed Ultrasound To Treat Brain Dysfunction on the Horizon

While other brain stimulation techniques involve surgical implantation or have significant adverse profile risks. William “Jamie” Tyler, from Arizona State University (Arizona, USA), and colleagues have pioneered a non-invasive transcranial pulsed ultrasound method that stimulates the brain, with the potential to treat brain injury and disease, and perhaps enhance cognitive abilities as well.   Employing a mouse model, the team used ultrasound to directly stimulate action potentials and drive intact brain activity without doing any kind of surgery. 

Yusuf Tufail, Alexei Matyushov, Nathan Baldwin, Monica L. Tauchmann, Joseph Georges, Anna Yoshihiro, Stephen I. Helms Tillery, William J. Tyler .  “Transcranial Pulsed Ultrasound Stimulates Intact Brain Circuits.” Neuron, 66(5) pp. 681 – 694, 10 June 2010.

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