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Omega-3s Inhibit Breast Cancer Progression

Mounting evidence suggests a diverse array of health effects of a diet rich in omega-3 fatty acids.  David W.L. Ma, from, the University of Guelph (Canada), and colleagues created a novel transgenic mouse that both produces omega-3 fatty acids and develops aggressive mammary tumors. The team compared those animals to mice genetically engineered only to develop the same tumors.  They found that the mice producing omega-3s developed only two-thirds as many tumors — and tumors were also 30%  smaller — as compared to controls.  The study authors submit that: “we provide, for the first time, unequivocal experimental evidence that [omega-3 fatty acids] is causally linked to tumor prevention.”

Mira B. MacLennan, Shannon E. Clarke, Kate Perez, Geoffrey A. Wood, William J. Muller, Jing X. Kang, David W.L. Ma.  “Mammary tumor development is directly inhibited by lifelong n-3 polyunsaturated fatty acids.”  The Journal of Nutritional Biochemistry, Volume 24, Issue 1, January 2013, Pages 388-395.

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