The menopause is associated with a relative lack of oestrogens and progestogens. Replacement therapy always requires oestrogens, which are given continuously. Cyclical progestogen is also required in women who have not had a hysterectomy. Progestogens are necessary to prevent hyperplasia (excessive formation of cells) and neoplasia (tumour cell formation) in the womb and to regulate any uterine bleeding that may occur. Oestrogens can be synthetic or purified from the urine of horses. A natural form of progestogen can also be used, but often it is not well tolerated because of drowsiness.
Source: http://www.healthandage.com/Home/gid7=123;jsessionid=4D36DF18FEB028ED84CFE748371529E2
[Editor: The preceding article was not written by A4M/WHN]