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HomeGeneticsGenetic ResearchHaploid Stem Cells Used to Create Human Genome Atlas

Haploid Stem Cells Used to Create Human Genome Atlas

 

Only one copy of the human genome are harbored in the new type of cell, making gene editing easier to conduct as only one copy of a target gene needs to be mutated, comparing to diploid cells wherein both gene copies need to be mutated.

 

Only 9% of all genes are required for embryonic stem cells to grow and survive, 5% of them limit their growth. Roles of genes which cause hereditary disorders during early development were examined, and demonstrated how oncogenes impact embryonic growth.

 

New functional views in how the human genome are provided by this gene atlas which is a tool that could change the manner by which cancer and other genetic disorders are analyzed. Scientists also identified a group of genes which are critical to survival of embryonic stem cells but no other cell types. New framework has been provided to better understand embryonic stem cells at genetic levels, bettering the chances for developing successful therapies.

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https://www.alphagalileo.org/en-gb/Item-Display/ItemId/162778

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