Exercise encourages cellular communications among bone, fat, and pancreatic cells. Norman Pollack, from Georgia Health Sciences University (Georgia, USA), and colleagues completed a study of obese children enrolled in after-school exercise programs. The researchers found that 12 weeks of vigorous exercise produced stronger bones, improved insulin sensitivity (reduced diabetes risk) and less of the most-deadly belly (visceral) fat. The team observed that blood levels of the hormone osteocalcin, made by bone-producing osteoblasts, were raised by vigorous exercise, and thereby may explain the response among bone, fat, and pancreatic cells.
Exercise Promotes Healthy Cellular Signals
Norman K Pollock; Paul J Bernard; Bernard Gutin; Catherine L Davis; Haidong Zhu; Yanbin Dong. “Adolescent obesity, bone mass, and cardiometabolic risk factors.” The Journal of Pediatrics 2011;158(5):727-34.