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Coffee Compound May Minimize Obesity-Related Disease

Previously, a number of studies suggest that coffee consumption may lower the risk for chronic diseases like Type 2 diabetes and cardiovascular disease.  Yongjie Ma, from the University of Georgia (Georgia, USA), and colleagues explored the role of chlorogenic acid, a compound found abundantly in coffee, for these effects.  Employing a mouse model that was fed ad high-fat diet for 15 weeks, the researchers concurrently administered thee animals with a chlorogenic acid solution twice per week. The team observed that the compound was effective in preventing weight gain, and also helped maintain normal blood sugar levels and healthy liver composition.  Writing that: “Our study provides direct evidence in support of [chlorogenic acid] as a potent compound in preventing diet-induced obesity and obesity-related metabolic syndrome,” the study authors submit that: “Our results suggest that drinking coffee is beneficial in maintaining metabolic homeostasis when on a high fat diet.”

Yongjie Ma, Mingming Gao, Dexi Liu.  “Chlorogenic Acid Improves High Fat Diet-Induced Hepatic Steatosis and Insulin Resistance in Mice.”  Pharmaceutical Research, 24 Sept. 2014.

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