Researchers have confirmed cinnamon’s antiproliferative and anti-angiogenic properties against cancer cells, particularly myeloma tumor cells.
RPMI 8226 human myeloma cancer cells were treated with 72 micrograms per milliliter of cinnamon bark powder extract, after 24 hours of treatment with cinnamon bark powder abstract was observed to have caused about 50% inhibition of cell growth in the cancer cell line; expression of angiogenic factors and cyclooxygenase was also suppressed at mRNA and protein levels in a time dependent manner; cell cycle arrest in the G0/G1 phase was also observed in a time dependent manner. Treatment caused fragmentation of cancer cell DNA which led to apoptosis, fragmentation increased with time, most fragmentation occurred 71 hours after treatment.
Researchers believe cinnamon may be a natural herbal source of treatment for cancer, and it was concluded that cinnamon has anti-cancer effects due to its ability to inhibit angiogenesis, induce apoptosis, and relieve inflammation.
