GENERAL DESCRIPTION:
Centrophenoxine is a compound of two chemicals: dimethylaminoethanol (DMAE), a compound
found naturally in food, especially fish, and
parachlorophenoxyacetate (pCPA), a synthetic compound
similar to a group of plant hormones called “auxins”.
Animal studies have found that centrophenoxine is effective
at removing lipofuscin (potassium age
pigment) from the brain, heart, and skin. Appearances of lipofuscin in the skin are referred to
as liver or age spots. Lipofuscin occurs in much higher
levels in Alzheimer’s patients than in their counterparts,
and some theories relate brain and memory function to
the ability of potassium to enter and exit brain cells. As we age, this ability is reduced and
potassium levels rise. There is also some evidence that
cells undergo apotosis (programmed cell death) when a
critical level of lipofuscin is present. Thus,
Centrophenoxine may help to preserve these cells.
Centrophenoxine can also increase production of brain RNA and aid in a patient’s oxygen consumption and carbon dioxide production.
ROLE FOR ANTI-AGING:
Centrophenoxine’s possible anti-aging
benefits include protection against free radical
damage in the brain, increased potential lifespan, reduction and prevention of age spots on
the skin, increased mental energy, improved memory and
learning ability, and prevention and treatment of stroke and
brain injury. Recently scientists have discovered
that centrophenoxine may be useful in alleviating
and preventing cognitive disturbances caused by fetal alcohol effects (FAE). A review
published in the Annals of the New York Academy of Sciences
in 2002 states that centrophenoxine treatment can prolong
the medium life span of laboratory animals, especially
when treatment is started at an early age. In some cases lifespan was increased by up to
30%, however such dramatic increases in lifespan were only
seen in animals treated with centrophenoxine from the
age of 6-months. Because of its low toxicity and potential positive effects in anti-aging, Centrophenoxine is considered to be an important
anti-aging supplement. In France it is viewed as a superior
DMAE product and is available over the
counter.
SIDE EFFECTS/CONTRAINDICATIONS:
Possible side effects may include nausea or
mild dizziness. People with severely high blood pressure or convulsive disorders such as
epilepsy should avoid Centrophenoxine.
PHARMACOLOGY: Synonyms:
Hydrochloride; Clofenoxine Hydrochloride; Clophenoxate
Hydrochloride; Deanol 4 Chlorophenoxyacetate Hydrochloride; Meclofenoxane
Hydrochloride.
Chemical Name: 2-Dimethylaminoethyl 4 chlorophynoxyacetate
hydrochloride.
Molecular Formula:
Molecular Weight:
Distribution:
is supplied in 250mg-tablet form under the trade names
Cerutil, Helfergin and Lucidri
