Taking supplementary anthocyanins, antioxidant pigments found in fruit and vegetables, may help people with high cholesterol to improve their lipid profile and reduce inflammation. Researchers from Sun Yat-Sen University and Shaoguan University in China recruited 150 people with high cholesterol for the double-blind, randomized study. Participants were randomly assigned to receive 320 mg of a purified anthocyanin mixture or a placebo for 24 weeks. Results showed that anthocyanin supplementation led to a 22% reduction in C-reactive protein (CRP) levels and a 12.3 % reduction in levels of soluble vascular cell adhesion molecule-1 (sVCAM-1), both of which are inflammatory compounds. Furthermore, LDL-cholesterol levels fell by 10% and HDL-cholesterol levels rose by 14% in those in the anthocyanin group, compared to a 0.3% increase in LDL and a 0.9% decrease in HDL in the control group. The researchers concluded: “Anthocyanin mixture reduced the inflammatory response in hypercholesterolemic subjects.”
Anthocyanins Slash Infammation and Improve Blood Lipid Profile
Zhu Y, Ling W, Guo H, et al. Anti-inflammatory effect of purified dietary anthocyanin in adults with hypercholesterolemia: A randomized controlled trial. Nutr Metab Cardiovasc Dis. 2012 Aug 17.
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