Sarah Pendlebury, from John Radcliffe Hospital (Oxford, United Kingdom), and colleagues analyzed 30 previously completed studies involving 7,511 people and published between 1950 and mid-year 2009. Reporting that “10% of patients had dementia before first stroke, 10% developed new dementia soon after first stroke, and more than a third had dementia after recurrent stroke,” the researchers comment that “first, there is a clear relationship between having multiple strokes and the risk of dementia; and secondly, the data suggest that the presence of complications after stroke [which may include high blood pressure, low oxygen saturation, cardiac events, and seizures] also increase the risk of developing dementia.”
Prevent Second Stroke to Ward Off Alzheimer’s Disease
Sarah T Pendlebury, Peter M Rothwell. “Prevalence, incidence, and factors associated with pre-stroke and post-stroke dementia: a systematic review and meta-analysis.” The Lancet Neurology, In Press, Corrected Proof, Available online 24 September 2009.
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