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Hydergine


GENERAL DESCRIPTION:


An important anti-aging and nootropic drug,
hydergine may help protect the brain
from free radical damage and oxygen starvation.
Hydergine maintains the brain’s optimal metabolism of oxygen. Oxygen is a free radical scavenger and generator. Free radicals cause
age-associated damage and at optimal levels oxygen will
neutralize more free radicals than it generates. Hydergine
may also stimulate the growth of dendrite nerve fibers, which may have a possible link to intelligence. Also, recent studies suggest that
hydergine may reduce Senescent Cell Antigen (SCA), a
destructive auto-antibody appearing more frequently in
elderly cells. SCA damages cells and finally destroys
them.


ROLE FOR ANTI-AGING:


Hydergine’s anti-aging benefits may include
protection from free radical damage, especially to the brain and the heart; protection from hypoxia
and peroxidation; prevention and treatment of strokes
and other brain injuries; increased potential lifespan; and
improved and extended periods of mental workloads. European studies on cats proved that
hydergine treated cats survived severe diminished blood and oxygen supply for much longer
periods than non-hydergine treated cats. Whereas cats in the
control group suffered brain damage within five minutes,
cats treated with hydergine survived 45 minutes later with strong brain wave patterns. Hydergine can also lower blood pressure, a Russian
study carried out in the year 2000 revealed that the drug
significantly lowered the blood pressure of hypertensive
menopausal women. The drug also helped to alleviate the symptoms of menopause.


SIDE EFFECTS/CONTRAINDICATIONS:


Mild side effects including nausea, headache, flushing of the skin, dizziness, and more
rarely, vomiting may occur with initial use. Stomach upset
may be more common with the tablet forms. Hydergine is synergistic with other nootropics, especially Piracetam and its analogues. Overall
dosage may need to be reduced.


PHARMACOLOGY:

Synonyms: Co-dergocrine
Mesilate; Co-dergocrine Methanesulphonate; Dihydroergotoxine Mesylate; Dihydroergotoxine
Methanesulphonate; Dihydrogenated Ergot Alkaloids; Ergoloid
Mesylates (USAN); hydrogenated Ergot Alkalids


Distribution:

Hydergine is supplied in 1mg, 1.5mg, 3mg, 4.5mg or 5mg tablets, and in sublingual liquid form where it is possible to take 0.5mg doses
at a time. There are many generics on the world market.
However, it remains generally accepted that the original
manufacturers of hydergine, Sandoz (now Novartis), manufacture the purest product.

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